Despite the mystery, many have theorized about Peter Gabriel’s relationship with actress Rosanna Arquette (via Daily Choices). She is well-known for her role in “Desperately Seeking Susan“ and “Pulp Fiction.” She and Gabriel were living together when his album “So” was released. At this time, Gabriel had not finalized his split from wife, Jill Moore. They officially divorced in 1987, according to RYM. This makes the relationship and the theory of her as the muse for “In Your Eyes” all the more scandalous. Gabriel and Arquette seemingly remained as a couple until 1992 (via Purple Clover). These are details that neither Gabriel nor Arquette have confirmed either, thus adding to the debates.
What does provide an argument in favor of “In Your Eyes” being written about Arquette is the fact that Say Anything director Cameron Crowe revealed that Arquette was integral in the song’s use for the film. Arquette brought the film to Gabriel’s attention. When speaking to Crowe on the phone, Gabriel relayed that “In Your Eyes” was a very personal song to him (via Entertainment Weekly). Given that he was living with Arquette when the song was first released and when Say Anything graced the theaters, many have concluded that “In Your Eyes” was written about Rosanna Arquette.